BTBD10 antibody (AA 301-400) (HRP)

Catalog No. ABIN1416730

This Rabbit Polyclonal antibody specifically detects BTBD10 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Rat.

Quick Overview for BTBD10 antibody (AA 301-400) (HRP) (ABIN1416730)

Target: BTBD10 (BTB (POZ) Domain Containing 10 (BTBD10))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD10 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BTBD10 Antibody (HRP)

Binding Specificity: AA 301-400

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BTBD10

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BTBD10

Target: BTBD10 (BTB (POZ) Domain Containing 10 (BTBD10))

Alternative Name: BTBD10

Background:

Synonyms: BTB broad complex tramtrack and bric a brac pox virus and zinc finger domain containing protein 10 , BTB POZ domain containing 10, BTB domain containing 10, BTB/POZ domain-containing protein 10, GMRP 1, GMRP1, K+ channel tetramerization protein, BTBDA_HUMAN.

Background: The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD10 (BTB (POZ) domain containing 10), also known as GMRP1, is a ubiquitously expressed nuclear protein found at highest levels in adult testis, brain and small intestine and weakly expressed in colon, lung, liver, kidney, spleen,pancreas, thymus, prostate, heart and ovary. Down-regulated in glioma, BTBD10 binds PP2A (protein phosphatase 2A) to inhibit dephosphorylation of Akts and is suggested to be a suppressor of cell death as well as an enhancer of cell growth. BTBD10 contains one BTB (POZ) domain and is encoded by a gene mapping to human chromosome 11p15.2.

Gene ID: 84280