BRIX1 antibody (AA 51-150) (HRP)

Catalog No. ABIN1416952

This Rabbit Polyclonal antibody specifically detects BRIX1 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for BRIX1 antibody (AA 51-150) (HRP) (ABIN1416952)

Target: BRIX1 (BRX1, Biogenesis of Ribosomes, Homolog (BRIX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRIX1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BRIX1 Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BXDC2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BRIX1

Target: BRIX1 (BRX1, Biogenesis of Ribosomes, Homolog (BRIX1))

Alternative Name: BXDC2

Background:

Synonyms: BRIX, Brix domain containing 2, Brix domain containing protein 2, BRIX1, BRX1, biogenesis of ribosomes, homolog S. cerevisiae, FLJ11100, Ribosome biogenesis protein Brix, BRX1_HUMAN.

Background: BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.

Gene ID: 55299