TSHZ3 antibody (AA 461-570) (Cy3)

Catalog No. ABIN1417481

The Rabbit Polyclonal anti-TSHZ3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect TSHZ3 in samples from Human.

Quick Overview for TSHZ3 antibody (AA 461-570) (Cy3) (ABIN1417481)

Target: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSHZ3 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TSHZ3 Antibody (Cy3)

Binding Specificity: AA 461-570

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSHZ3/ZNF537

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSHZ3

Target: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Alternative Name: ZNF537

Background:

Synonyms: teashirt homolog 3, Zinc finger protein 537, TSHZ3, TSH3, ZNF537, TSH3_HUMAN.

Background: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. TSHZ3 (teashirt zinc finger homeobox 3), also known as KIAA1474, TSH3 or ZNF537, is a 1,081 amino acid protein that contains one homeobox DNA-binding domain and five C2H2-type zinc fingers. Localized to the nucleus, TSHZ3 functions as a transcriptional regulator that is involved in developmental processes throughout the body. The gene encoding TSHZ3 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.

Gene ID: 57616

Pathways: Regulation of Muscle Cell Differentiation