DOK5 antibody (AA 21-120) (HRP)

Catalog No. ABIN1417762

This Rabbit Polyclonal antibody specifically detects DOK5 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for DOK5 antibody (AA 21-120) (HRP) (ABIN1417762)

Target: DOK5 (Docking Protein 5 (DOK5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DOK5 Antibody (HRP)

Binding Specificity: AA 21-120

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOK5/IRS6

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5

Background:

Synonyms: IRS6, IRS-6, C2orf18, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, DOK5

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

Gene ID: 55816

UniProt: Q9P104