DOK5 antibody (AA 21-120)

Catalog No. ABIN1387610

There is 1 publication for this product available. The Rabbit Polyclonal anti-DOK5 antibody is suitable to detect DOK5 in samples from Human. It has been validated for FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for DOK5 antibody (AA 21-120) (ABIN1387610)

Target: DOK5 (Docking Protein 5 (DOK5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DOK5 Antibody

Binding Specificity: AA 21-120

Purpose: DOK5 Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOK5/IRS6

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-DOK5 antibody (ABIN1387610)

Pan, Zhang, Liu, Shu, Yin, Yuan, Qiang, Peng: "Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis." in: Neuroscience letters, Vol. 553, pp. 46-51, (2013) (PubMed).

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: DOK5

Background:

Synonyms: IRS6, IRS-6, C2orf18, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, DOK5

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

Gene ID: 55816

UniProt: Q9P104