SMS antibody (AA 245-350) (HRP)

Catalog No. ABIN1418020

This Rabbit Polyclonal antibody specifically detects SMS in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for SMS antibody (AA 245-350) (HRP) (ABIN1418020)

Target: SMS (Spermine Synthase, SMS (SMS))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMS antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SMS Antibody (HRP)

Binding Specificity: AA 245-350

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Spermine synthase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SMS

Target: SMS (Spermine Synthase, SMS (SMS))

Alternative Name: Spermine synthase

Background:

Synonyms: MRSR, SMS, Snyder Robinson X linked mental retardation syndrome, Spermidine aminopropyltransferase, Spermine synthase, SPMSY, SpS, SPSY_HUMAN, SRS.

Background: Spermine synthase catalyzes the production of spermine from spermidine. Spermine, a polyamine ubiquitously present in most organisms, is essential for normal cell growth and differentiation. Because absence of spermine increases sensitivity of cells to anti-tumor agents, spermine synthase (and other polyamine biosynthesis) is an attractive target for anti-neoplastic therapy.