ANKS1B antibody (Cy5.5)

Catalog No. ABIN1418689

This Rabbit Polyclonal antibody specifically detects ANKS1B in WB and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ANKS1B antibody (Cy5.5) (ABIN1418689)

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKS1B antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ANKS1B Antibody (Cy5.5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANKS1B

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Alternative Name: ANKS1B

Background:

Synonyms: AIDA 1, AIDA-1, Amyloid-beta protein intracellular domain-associated protein 1, Anks1b, Ankyrin repeat and sterile alpha mot domain-containing protein 1B, ANS1B_HUMAN, E2A-PBX1-associated protein, EB-1.

Background: The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer?s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.

Gene ID: 56899

UniProt: Q7Z6G8