ASB13 antibody (Cy5)

Catalog No. ABIN1418742

This anti-ASB13 antibody is a Rabbit Polyclonal antibody detecting ASB13 in IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for ASB13 antibody (Cy5) (ABIN1418742)

Target: ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB13 antibody is conjugated to Cy5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ASB13 Antibody (Cy5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASB13

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ASB13

Target: ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))

Alternative Name: ASB13

Background:

Synonyms: Ankyrin repeat and SOCS box containing 13, Ankyrin repeat and SOCS box containing protein 13, Ankyrin repeat and SOCS box protein 13, Ankyrin repeat domain containing SOCS box protein Asb 13, Ankyrin repeat domain containing SOCS box protein Asb13, ASB 13, ASB13_HUMAN.

Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-13 (ankyrin repeat and SOCS box-containing 13) is a 278 amino acid member of the ASB family that contains one SOCS box domain and six ANK repeats. Existing as multiple isoforms, ASB-13 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene ID: 79754