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ATAD3A antibody (HRP)

This Rabbit Polyclonal antibody specifically detects ATAD3A in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN1418758

Quick Overview for ATAD3A antibody (HRP) (ABIN1418758)

Target

See all ATAD3A Antibodies
ATAD3A (ATPase Family, AAA Domain Containing 3A (ATAD3A))

Reactivity

  • 32
  • 20
  • 18
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 30
  • 2
Rabbit

Clonality

  • 32
Polyclonal

Conjugate

  • 16
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATAD3A antibody is conjugated to HRP

Application

  • 29
  • 13
  • 9
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Cross-Reactivity

    Human, Mouse, Rat

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ATAD3A

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handling Advice

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    ATAD3A (ATPase Family, AAA Domain Containing 3A (ATAD3A))

    Alternative Name

    ATAD3A

    Background

    Synonyms: AAA-ATPase TOB3, ATAD3B, ATAD3C, Atad3a, ATPase family AAA domain containing protein 3A, ATPase family AAA domain-containing protein 3, ATPase family, AAA domain containing 3A, FLJ10709, FLJ35514, AAA ATPase TOB3, AAA-TOB3, ATPase family AAA domain containing protein 3B, ATPase family, AAA domain containing 3B, ATPase family, AAA domain containing, member 3B, TOB3, ATD3A_HUMAN, ATAD3A/B/C.

    Background: The AAA ATPase family of molecular chaperones are characterized by a highly conserved AAA motif. Composed of 200-250 residues, the AAA domain contains Walker homology sequences and imparts ATPase activity. Members of the AAA ATPase family act as DNA helicases as well as transcription factors and are thought to be involved in several cellular functions such as cell-cycle regulation, protein proteolysis, organelle biogenesis and vesicle-mediated protein transport. Mitochondrial membrane proteins ATAD3A and ATAD3B contribute to the stabilization of nucleoids which are large mitochondrial DNA (mtDNA)-protein complexes. ATAD3A/B may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The genes encoding ATAD3A/B/C maps to human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome.

    Gene ID

    55210
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