TRIM36 antibody (HRP)

Catalog No. ABIN1419022

This Rabbit Polyclonal antibody specifically detects TRIM36 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRIM36 antibody (HRP) (ABIN1419022)

Target: TRIM36 (Tripartite Motif Containing 36 (TRIM36))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM36 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRIM36 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRIM36/RNF98

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRIM36

Target: TRIM36 (Tripartite Motif Containing 36 (TRIM36))

Alternative Name: RNF98

Background:

Synonyms: Acrosome RBCC protein, E3 ubiquitin protein ligase TRIM36, E3 ubiquitin-protein ligase Trim36, Haprin, RBCC728, Ring finger protein 98, TRI36_HUMAN, TRIM 36, TRIM36, Tripartite mot containing 36, Tripartite mot containing protein 36, Tripartite mot protein 36, Tripartite mot-containing protein 36, Zinc binding protein Rbcc728, Zinc-binding protein Rbcc728.

Background: TRIM36 (tripartite motif-containing 36), also known as RNF98 (RING finger protein 98), HAPRIN (haploid germ cell-specific RBCC protein) or RBCC728, is a 728 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. Predominantly expressed in prostate, testis and brain with weak expression in heart, kidney and lung, TRIM36 contains two B box-type zinc fingers, a SPRY domain, a coiled-coil domain, a fibronectin type-III domain and a RING-type zinc finger, a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. Localizing to the cytoplasm and the acrosomal region of germ cells and mature sperm, TRIM36 is believed to play a role in the acrosome reaction and fertilization. In addition, TRIM36 is overexpressed in prostate cancer, suggesting a possible role for TRIM36 in prostate tumorigenesis.

Gene ID: 55521