IGSF10 antibody (HRP)

Catalog No. ABIN1419292

This Rabbit Polyclonal antibody specifically detects IGSF10 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for IGSF10 antibody (HRP) (ABIN1419292)

Target: IGSF10 (Immunoglobulin Superfamily, Member 10 (IGSF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF10 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IGSF10 Antibody (HRP)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGSF10

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IGSF10

Target: IGSF10 (Immunoglobulin Superfamily, Member 10 (IGSF10))

Alternative Name: IGSF10

Background:

Synonyms: Adlican2, Calvaria mechanical force protein 608, CMF608, IGS10_HUMAN, IgSF10, Immunoglobulin superfamily member 10.

Background: Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation. The gene encoding IGSF10 maps to chromosome 3, which comprises over 1,100 genes that include a chemokine receptor gene cluster as well as a variety of human cancer related loci.

Gene ID: 285313