ARHGAP32 antibody (AA 860-896) (HRP)

Catalog No. ABIN1419772

This Rabbit Polyclonal antibody specifically detects ARHGAP32 in IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ARHGAP32 antibody (AA 860-896) (HRP) (ABIN1419772)

Target: ARHGAP32 (rho GTPase Activating Protein 32 (ARHGAP32))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP32 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ARHGAP32 Antibody (HRP)

Binding Specificity: AA 860-896

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARHGAP32

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ARHGAP32

Target: ARHGAP32 (rho GTPase Activating Protein 32 (ARHGAP32))

Alternative Name: ARHGAP32

Background:

Synonyms: GRIT, RICS, GC-GAP, PX-RICS, p250GAP, p200RhoGAP, Rho GTPase-activating protein 32, Brain-specific Rho GTPase-activating protein, GAB-associated Cdc42/Rac GTPase-activating protein, GTPase regulator interacting with TrkA, Rho-type GTPase-activating protein 32, Rho/Cdc42/Rac GTPase-activating protein RICS, RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling, ARHGAP32, KIAA0712

Background: GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity).

Gene ID: 9743

UniProt: A7KAX9