C9orf153 antibody (HRP)

Catalog No. ABIN1420942

This Rabbit Polyclonal antibody specifically detects C9orf153 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for C9orf153 antibody (HRP) (ABIN1420942)

Target: C9orf153 (Chromosome 9 Open Reading Frame 153 (C9orf153))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9orf153 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C9orf153 Antibody (HRP)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf153

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C9orf153

Target: C9orf153 (Chromosome 9 Open Reading Frame 153 (C9orf153))

Alternative Name: C9orf153

Background:

Synonyms: bA507D14.1, Chromosome 9 open reading frame 153, Hypothetical protein LOC389766, MGC131702, Uncharacterized protein C9orf153,

Background: C9orf153 is a 101 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding C9orf153 maps to human chromosome 9q21.33. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 389766