Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 30-80) antibody (HRP)

Catalog No. ABIN1421158

This Rabbit Polyclonal antibody specifically detects in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 30-80) antibody (HRP) (ABIN1421158)

Target: Chromosome 6 Open Reading Frame 134 (C6orf134)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 30-80

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human alpha-TAT

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Chromosome 6 Open Reading Frame 134 (C6orf134)

Alternative Name: alpha-TAT

Background:

Synonyms: C6orf134, Acetyltransferase mec 17 homolog, Alpha TAT, Alpha tubulin acetyltransferase 1, Alpha tubulin N acetyltransferase, Chromosome 6 open reading frame 134, Hypothetical protein LOC79969, MEC17, Nbla00487, TAT, ATAT_HUMAN.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf134 gene product has been provisionally designated C6orf134 pending further characterization.

Gene ID: 79969

UniProt: Q5SQI0