TSSK6 antibody (HRP)

Catalog No. ABIN1422226

This Rabbit Polyclonal antibody specifically detects TSSK6 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TSSK6 antibody (HRP) (ABIN1422226)

Target: TSSK6 (Testis-Specific Serine Kinase 6 (TSSK6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSSK6 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TSSK6 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSSK6/CT72

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSSK6

Target: TSSK6 (Testis-Specific Serine Kinase 6 (TSSK6))

Alternative Name: TSSK6

Background:

Synonyms: Cancer/testis antigen 72, CT72, EC 2.7.11.1, Serine/threonine-protein kinase SSTK, Small serine/threonine kinase, Small serine/threonine protein kinase, SSTK, testis-specic serine kinase 6, Testis-specic serine/threonine kinase 6, Testis-specic serine/threonine-protein kinase 6, TSK 6, TSSK4, TSSK6_HUMAN.

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.

Gene ID: 83983