C10orf93 antibody (HRP)

Catalog No. ABIN1422448

This Rabbit Polyclonal antibody specifically detects C10orf93 in IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for C10orf93 antibody (HRP) (ABIN1422448)

Target: C10orf93 (TTC40) (Tetratricopeptide Repeat Domain 40 (TTC40))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C10orf93 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C10orf93 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C10orf93

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C10orf93

Target: C10orf93 (TTC40) (Tetratricopeptide Repeat Domain 40 (TTC40))

Alternative Name: C10orf93

Background:

Synonyms: TTC40, C10orf92, C10orf93, C10orf123, C10orf124, bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, Protein CFAP46, Cilia- and flagella-associated protein 46, Tetratricopeptide repeat protein 40, CFAP46

Background: C10orf93 , also known as C10orf124 or TPR repeat-containing protein C10orf93, is a 1,530 amino acid protein that contains two TPR repeats and exists as three alternatively spliced isoforms. The gene encoding C10orf93 maps to human chromosome 10q26.3. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Gene ID: 54777

UniProt: Q8IYW2