TRMT1L antibody (HRP)

Catalog No. ABIN1422520

This Rabbit Polyclonal antibody specifically detects TRMT1L in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRMT1L antibody (HRP) (ABIN1422520)

Target: TRMT1L (TRM1 tRNA Methyltransferase 1-Like (TRMT1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT1L antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRMT1L Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf25

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TRMT1L

Target: TRMT1L (TRM1 tRNA Methyltransferase 1-Like (TRMT1L))

Alternative Name: C1orf25

Background:

Synonyms: bG120K12.3, Chromosome 1 open reading frame 25, Hypothetical protein FLJ90512, MST070, MSTP070, N2 antibody N2 dimethylguanosine tRNA methyltransferase like, TRM1L_HUMAN, TRMT1-like protein, Trmt1l.

Background: C1orf25, also known as TRM1L (TRMT1-like protein), MST070 or MSTP070, is a 733 amino acid protein that belongs to the TRM1 family of proteins. Expressed in a wide variety of tissues, C1orf25 contains one C2H2-type zinc finger and shares sequence similarity with TRMT1, a tRNA methyltransferase that dimethylates guanine at position 26 of tRNAs. As is suggested by observations of C1orf25-deficient mice, C1orf25 is believed to play a role in exploratory behavior and motor coordination. The gene encoding C1orf25 localizes to chromosome 1 and, due to alternative splicing events, C1orf25 exists as at least two isoforms.

Gene ID: 81627