TCN2 antibody (HRP)

Catalog No. ABIN1423312

This Rabbit Polyclonal antibody specifically detects TCN2 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TCN2 antibody (HRP) (ABIN1423312)

Target: TCN2 (Transcobalamin II (TCN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCN2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TCN2 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCN2/Transcobalamin II

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TCN2

Target: TCN2 (Transcobalamin II (TCN2))

Alternative Name: TCN2

Background:

Synonyms: Macrocytic anemia, TC, TC II, TC-2, TC2, TCII, TCN 2, TCO2_HUMAN, Transcobalamin 2, Transcobalamin II, Transcobalamin II, macrocytic anemia, Transcobalamin-2, Vitamin B12 binding protein 2.

Background: Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions.

Gene ID: 6948