C11ORF71 antibody (HRP)

Catalog No. ABIN1423444

This Rabbit Polyclonal antibody specifically detects C11ORF71 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for C11ORF71 antibody (HRP) (ABIN1423444)

Target: C11ORF71 (Chromosome 11 Open Reading Frame 71 (C11ORF71))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11ORF71 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C11ORF71 Antibody (HRP)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11orf71

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C11ORF71

Target: C11ORF71 (Chromosome 11 Open Reading Frame 71 (C11ORF71))

Alternative Name: C11orf71

Background:

Synonyms: C11orf71 chromosome 11 open reading frame 71, CK071_HUMAN, FLJ20010, Gm5617, hypothetical protein LOC54494, Uncharacterized protein C11orf71.

Background: C11orf71, also known as FLJ20010, is a 123 amino acid protein that exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gene ID: 54494