CWH43 antibody (AA 540-590) (HRP)

Catalog No. ABIN1423552

This Rabbit Polyclonal antibody specifically detects CWH43 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CWH43 antibody (AA 540-590) (HRP) (ABIN1423552)

Target: CWH43 (Cell Wall Biogenesis 43 C-Terminal Homolog (CWH43))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CWH43 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CWH43 Antibody (HRP)

Binding Specificity: AA 540-590

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CWH43

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CWH43

Target: CWH43 (Cell Wall Biogenesis 43 C-Terminal Homolog (CWH43))

Alternative Name: CWH43

Background:

Synonyms: Cell wall biogenesis protein 43 C-terminal homolog, Cwh43, imds 60, PG2IP_HUMAN, PGAP2-interacting protein, CWH43-C, PGAP2IP

Background: Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The CWH43 gene product has been provisionally designated CWH43 pending further characterization.

Gene ID: 80157

UniProt: Q9H720

Pathways: Inositol Metabolic Process