alpha Estradiol antibody (HRP)

Catalog No. ABIN1423762

This Mouse Monoclonal antibody specifically detects in IHC (p). It exhibits reactivity toward .

Quick Overview for alpha Estradiol antibody (HRP) (ABIN1423762)

Target: alpha Estradiol

Host: Mouse

Clonality: Monoclonal

Conjugate: HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2G2

Product Details

Cross-Reactivity (Details): alpha Estradiol

Purification: Purified by Protein G.

Immunogen: KLH conjugated alpha Estradiol

Isotype: IgG

Application Details

Application Notes: IHC-P 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: alpha Estradiol

Target Type: Hormone

Background:

Synonyms: 1,3,510-Estratriene-3,17alpha-diol, 3,17 alpha-Dihydroxy-1,3,510-estratriene, Epiestradiol, alpha Estradiol, 17 alpha Estradiol, Ethynyl Estradiol, Oestradiol, Estradial, Ovocylin.

Background: Estradiol (known as alpha Estradiol or 17 alpha Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture.17-estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer?s disease and ischemic stroke.