Astrotactin 2 antibody (PE-Cy7)

Catalog No. ABIN1424679

This anti-Astrotactin 2 antibody is a Rabbit Polyclonal antibody detecting Astrotactin 2 in WB. Suitable for Human, Mouse, Rat and Cow.

Quick Overview for Astrotactin 2 antibody (PE-Cy7) (ABIN1424679)

Target: Astrotactin 2 (ASTN2)

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Astrotactin 2 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-Astrotactin 2 Antibody (PE-Cy7)

Predicted Reactivity: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASTN2

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Astrotactin 2

Target: Astrotactin 2 (ASTN2)

Alternative Name: ASTN2

Background:

Synonyms: Astn2, Astn-2, Astn 2, ASTN2_HUMAN, Astrotactin 2, Astrotactin2, Astrotactin-2, bA67K19.1, KIAA0634.

Background: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.

Molecular Weight: 143kDa