PCDHb4 antibody (PE)

Catalog No. ABIN1425005

The Rabbit Polyclonal anti-PCDHb4 antibody has been validated for . It is suitable to detect PCDHb4 in samples from Human, Mouse and Rat.

Quick Overview for PCDHb4 antibody (PE) (ABIN1425005)

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHb4 antibody is conjugated to PE

Application: Please inquire

Product Details anti-PCDHb4 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB4

Isotype: IgG

Application Details

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for PCDHb4

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Alternative Name: Pcdhb4

Background:

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain.

Subcellular location: Extracellular

Synonyms: PCDB4_HUMAN, PCDH beta4, PCDH-beta-4, PCDHB4, PCDHB 4, PCDHB-4, Pcdhb5A, PcdhbD, Protocadherin beta-4.