Protocadherin gamma Subfamily C, 3 (PCDHGC3) antibody (PE-Cy7)

Catalog No. ABIN1425114

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB. Suitable for Human, Rat and Mouse.

Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) antibody (PE-Cy7) (ABIN1425114)

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: PE-Cy7

Application: Western Blotting (WB)

Product Details

Predicted Reactivity: Human,Mouse,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHGC3/PCDH2

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Alternative Name: PCDHGC3/PCDH2

Background:

Synonyms: Cadherin like 2, PC 43, PC43, PCDH 2, PCDH gamma C3, PCDH2, PCDHGC 3, Protocadherin 2, Protocadherin 43, Protocadherin gamma C3, Protocadherin gamma subfamily C 3, Protocadherin43, PCDGK_HUMAN.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH2 (protocadherin-2), also known as PCDHGC3 (protocadherin gamma subfamily C, 3) or PC43, is a 934 amino acid single-pass type I membrane protein that contains six cadherin domains and belongs to the protocadherin gamma family. Functioning as a calcium-dependent cell-adhesion protein, PCDH2 is thought to be involved in the establishment and maintenance of neuronal connections within the brain. Multiple isoforms of PCDH2 exist due to alternative splicing events.

Molecular Weight: 101kDa