NETO2 antibody (PE)

Catalog No. ABIN1428730

This Rabbit Polyclonal antibody specifically detects NETO2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NETO2 antibody (PE) (ABIN1428730)

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NETO2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-NETO2 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NETO2

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for NETO2

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Alternative Name: Neto2

Background:

NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Subcellular location: Extracellular

Synonyms: Brain specic transmembrane protein, Brain specic transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2, Brain-specic transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, FLJ10430, FLJ14724, FLJ90456, NEOT2, NETO 2, Neto2, NETO2_HUMAN, Neuropilin NRP and tolloid TLL like 2, Neuropilin and tolloid like protein 2, Neuropilin and tolloid-like protein 2.