NETO2 antibody (N-Term)

Catalog No. ABIN2782942

This Rabbit Polyclonal antibody specifically detects NETO2 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Horse and Dog.

Quick Overview for NETO2 antibody (N-Term) (ABIN2782942)

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NETO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NETO2 Antibody

Binding Specificity: N-Term

Purpose: NETO2 Antibody - N-terminal region

Sequence: ELSGADGIVR SSQVEQEEKT KPGQAVDCIW TIKATPKAKI YLRFLDYQME

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NETO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NETO2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP47391-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NETO2

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Alternative Name: NETO2

Background:

Background Information: NETO2 is a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis.This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis. Alternatively spliced transcript variants have been observed, but they have not been fully characterized.

Gene Name: Neuropilin (NRP) and tolloid (TLL)-like 2

Alternative Symbols: BTCL2, NEOT2

Protein Name: Neuropilin and tolloid-like protein 2

Molecular Weight: 57kDa

Gene ID: 81831

NCBI Accession: NP_060562

UniProt: Q8NC67