SLITRK4 antibody (PE)

Catalog No. ABIN1429020

This anti-SLITRK4 antibody is a Rabbit Polyclonal antibody detecting SLITRK4 in FACS. Suitable for Human, Mouse and Rat.

Quick Overview for SLITRK4 antibody (PE) (ABIN1429020)

Target: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-SLITRK4 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLITRK4

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for SLITRK4

Target: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Alternative Name: Slitrk4

Background:

SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, specifically in the thalamus, hypothalamus, subventricular zone, CA3 region of the hippocampus and cortical plate. SLITRK4 may be upregulated in some astrocytic brain tumors such as glioblastomas, astrocytomas and primitive neuroectodermal tumors. As compared with its family member SLITRK2, SLITRK4 only weakly suppresses neurite outgrowth. A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, as well as the ARL5B and PLA2G7 genes, may be involved in the pathogenesis of preeclampsia.

Subcellular location: Extracellular

Synonyms: DKFZp547M2010, SLIK4_HUMAN, SLIT and NTRK like family member 4, SLIT and NTRK like protein 4, SLIT and NTRK-like protein 4, Slit and trk like 4 protein, Slit and trk like gene 4, SLITRK 4, SLITRK4.