TMEM132A antibody (PE)

Catalog No. ABIN1429565

The Rabbit Polyclonal anti-TMEM132A antibody has been validated for FACS. It is suitable to detect TMEM132A in samples from Human, Mouse and Rat.

Quick Overview for TMEM132A antibody (PE) (ABIN1429565)

Target: TMEM132A (Transmembrane Protein 132A (TMEM132A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM132A antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-TMEM132A Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMEM132A

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for TMEM132A

Target: TMEM132A (Transmembrane Protein 132A (TMEM132A))

Alternative Name: Tmem132a

Background:

TMEM132A is a 560 amino acid protein encoded by a gene mapping to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and â^ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Subcellular location: Extracellular

Synonyms: GBP, HSPA5-binding protein 1, HSPA5BP1, T132A_HUMAN, Tmem132a, Transmembrane protein 132A.