NLRX1 antibody (PE-Cy5)

Catalog No. ABIN1433304

This anti-NLRX1 antibody is a Rabbit Polyclonal antibody detecting NLRX1 in WB. Suitable for Human, Rat, Mouse, Dog, Cow and Pig.

Quick Overview for NLRX1 antibody (PE-Cy5) (ABIN1433304)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRX1 antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Product Details anti-NLRX1 Antibody (PE-Cy5)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLR family member X1

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Alternative Name: NLRX1

Background:

Synonyms: NOD5, NOD9, NOD26, DLNB26, CLR11.3, NLR family member X1, Caterpiller protein 11.3, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9, NLRX1

Background: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Molecular Weight: 108kDa

Gene ID: 79671

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome