STIM1 antibody (PE)

Catalog No. ABIN1433377

This Rabbit Polyclonal antibody specifically detects STIM1 in IF (p). It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Pig and Chicken.

Quick Overview for STIM1 antibody (PE) (ABIN1433377)

Target: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STIM1 antibody is conjugated to PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-STIM1 Antibody (PE)

Cross-Reactivity: Rat (Rattus), Chicken, Dog (Canine), Pig (Porcine), Cow (Bovine)

Purification: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human STIM1

Isotype: IgG

Application Details

Comment:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4 °C for 12 months

Expiry Date: 12 months

Target Details for STIM1

Target: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Alternative Name: STIM1

Background: Plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.

Molecular Weight: 73kDa

Gene ID: 6786

HGNC: 0

Pathways: TCR Signaling, BCR Signaling