RAB3A antibody (C-Term)

Catalog No. ABIN1440023

There is 1 publication for this product available. The Goat Polyclonal anti-RAB3A antibody is suitable to detect RAB3A in samples from Human, Rat, Mouse, Dog, Cow, Guinea Pig, Sheep, Monkey, Pig, Hamster, Cat, Chicken, Donkey, Goat, Avian, Horse and Rabbit. It has been validated for WB, IF, IHC (p) and IHC (fro).

Quick Overview for RAB3A antibody (C-Term) (ABIN1440023)

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Sheep, Monkey, Pig, Hamster, Cat, Chicken, Donkey, Goat, Avian, Horse, Rabbit

Host: Goat

Clonality: Polyclonal

Conjugate: This RAB3A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RAB3A Antibody

Binding Specificity: C-Term

Purpose: Anti-Rab3

Specificity: Detects total Rab3 protein in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab3a, GFP-Rab3b, and GFP-Rab3c cds by Western blot.

Characteristics: RAB3, member RAS oncogene family

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptides derived from within residues 110 aa to the C-terminus of mouse Rab3a produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:250-1:1,000, IF:1:50-1:250, IHC-P:1:250-1:500, IHC-F:1:250-1:500

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

References for anti-RAB3A antibody (ABIN1440023)

Encarnação, Espada, Escrevente, Mateus, Ramalho, Michelet, Santarino, Hsu, Brenner, Barral, Vieira: "A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair." in: The Journal of cell biology, Vol. 213, Issue 6, pp. 631-40, (2017) (PubMed).

Target Details for RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Alternative Name: Rab3

Background:

Goat polyclonal antibody to mouse Rab3. Rab3 belongs to the small GTPase superfamily, Rab family. Rab3 is involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.

RAB3A, RAB3B, RAB3C, RAB3D, RAS-associated protein RAB3A, ras-related protein Rab-3B, RAS-associated protein RAB3C, RAS-associated protein RAB3D, ras-related protein Rab-3A, ras-related protein Rab-3B, ras-related protein Rab-3C, ras-related protein Rab-3D antibody.

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport