Caveolin-1 antibody (N-Term)

Catalog No. ABIN1440030

The Goat Polyclonal anti-Caveolin-1 antibody (ABIN1440030) specifically detects Caveolin-1 in WB, IF, IHC (p) and IHC (fro). The antibody is reactive with Human, Rat, Mouse, Dog, Pig, Cow, Sheep, Rabbit, Monkey, Horse, Guinea Pig, Chicken, Goat, Avian, Cat, Donkey and Hamster samples.

Quick Overview for Caveolin-1 antibody (N-Term) (ABIN1440030)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Sheep, Rabbit, Monkey, Horse, Guinea Pig, Chicken, Goat, Avian, Cat, Donkey, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Caveolin-1 Antibody

Binding Specificity: N-Term

Purpose: Anti-CAV1

Sequence: MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID LVNRDPKHLN DDVVKIDFED VIAEPEGTH

Specificity: Detects a band of approximately 25 kDa by Western blot in the following cell lysate: hCat, MDCK and 3T3.

Characteristics: Caveolin-1

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 100 aa to the N-terminus of human CAV1 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000, IF:1:25-1:250, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000

Restrictions: For Research Use only

Handling

Concentration: 2 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: CAV1

Background:

Goat polyclonal to Caveolin-1 - caveolae marker. This scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression.

CAV1, caveolin, caveolae protein 1, cell growth-inhibiting protein 32 antibody.

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals