KPNA3 antibody

Catalog No. ABIN1449200

The Rat Monoclonal anti-KPNA3 antibody is suitable to detect KPNA3 in samples from Human, Mouse, Rat and Hamster. It has been validated for WB.

Quick Overview for KPNA3 antibody (ABIN1449200)

Target: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rat

Clonality: Monoclonal

Conjugate: This KPNA3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3D10

Product Details anti-KPNA3 Antibody

Specificity: This antibody reacts with Importin α3.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat, Hamster

Purification: Protein G agarose

Immunogen: Human recombinant full-length Importin alpha3

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store (in aliqouts) at -20 °C.

Target Details for KPNA3

Target: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Alternative Name: KPNA3 / Importin alpha-3

Background: Functional nuclear proteins are selectively imported into the nucleus by transport factors such as importins a and ß. Importin a, which mediates the nuclear import of nuclear localization signal (NLS)-containing proteins, is a member of nuclear transport factors. Importin a binds directly NLS and functions as an adapter for accessing the importin ß-dependent import pathway. The import complex is translocated through the nuclear pore complex by interactions of importin ß with a series of nucleoporins.Synonyms: Importin alpha Q2, Karyopherin subunit alpha-3, QIP2, SRP1-gamma

Molecular Weight: 60 kDa

Gene ID: 3839

NCBI Accession: NP_002258

UniProt: O00505

Pathways: Protein targeting to Nucleus