Stabilin 2 (STAB2) antibody

Catalog No. ABIN1449211

Product Details

Target: Stabilin 2 (STAB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts with FEEL-2.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogen: Membrane fraction of FEEL-2 transfectant

Clone: 17

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store (in aliqouts) at -20 °C.

Target Details

Target: Stabilin 2 (STAB2)

Alternative Name: Stabilin 2 / STAB2 (STAB2 Products)

Background: Advanced Glycation End Products (AGEs) are nonenzymatically glycosylated proteins and lipids that accumulate in vascular tissues in aging and diabetes. FEEL-1 (fasciclin, epidermal growth factor (EGF)-like, laminin-type EGF-like, and link domain-containing scavenger receptor-1) and FEEL-2 are an approximately 280 kDa protein that serves as an endocytic receptor for AGEs. FEEL-2 is a paralogous gene of FEEL-1 whose amino acid sequence is about 40 % identical to FEEL-1. Quantitative PCR analyses showed that both FEEL-1 and FEEL-2 are expressed in the spleen and lymph node and liver.Synonyms: EGF-like, FEEL-2, FEEL2, FELL, FEX2, Fasciclin, HARE, Stabilin-2, laminin-type EGF-like and link domain-containing scavenger receptor 2

Molecular Weight: 280 kDa

Gene ID: 55576

NCBI Accession: NP_060034

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process