MEMO1 antibody (N-Term)

Catalog No. ABIN1449397

This Mouse Monoclonal antibody specifically detects MEMO1 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for MEMO1 antibody (N-Term) (ABIN1449397)

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEMO1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1E9

Product Details anti-MEMO1 Antibody

Binding Specificity: AA 1-297, N-Term

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human MEMO1 (1-297aa) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Alternative Name: MEMO1

Background: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activitySynonyms: C21orf19-like protein, C2orf4, CGI-27, HCV NS5A-transactivated protein 7, Hepatitis C virus NS5A-transactivated protein 7, Mediator of ErbB2-driven cell motility 1, NS5ATP7

Gene ID: 51072

NCBI Accession: NP_057039

UniProt: Q9Y316