ABCA7 antibody (N-Term)

Catalog No. ABIN1449921

The Rabbit Polyclonal anti-ABCA7 antibody (ABIN1449921) specifically detects ABCA7 in WB, IF and EIA. The antibody is reactive with Human samples.

Quick Overview for ABCA7 antibody (N-Term) (ABIN1449921)

Target: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCA7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-ABCA7 Antibody

Binding Specificity: N-Term

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the amino terminus of Human ABCA7

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ABCA7

Target: ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))

Alternative Name: ABCA7

Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.Synonyms: ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, Macrophage ABC transporter

Gene ID: 10347

NCBI Accession: NP_061985