EED antibody (N-Term)

Catalog No. ABIN1449991

This Rabbit Polyclonal antibody specifically detects EED in WB, IF and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EED antibody (N-Term) (ABIN1449991)

Target: EED (Embryonic Ectoderm Development (EED))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EED antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-EED Antibody

Binding Specificity: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: EED antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of Human EED

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EED

Target: EED (Embryonic Ectoderm Development (EED))

Alternative Name: Polycomb Protein EED

Background: The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin beta7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.Synonyms: EED, WAIT-1, WAIT1, WD protein associating with integrin cytoplasmic tails 1, embryonic ectoderm development, hEED

Molecular Weight: 49 kDa

Gene ID: 8726

NCBI Accession: NP_003788