VPS51 antibody (C-Term)

Catalog No. ABIN1450001

The Rabbit Polyclonal anti-VPS51 antibody has been validated for WB and EIA. It is suitable to detect VPS51 in samples from Human, Mouse and Rat.

Quick Overview for VPS51 antibody (C-Term) (ABIN1450001)

Target: VPS51 (Vacuolar Protein Sorting 51 Homolog (VPS51))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS51 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-VPS51 Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: Fat Free antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of Human Fat Free

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for VPS51

Target: VPS51 (Vacuolar Protein Sorting 51 Homolog (VPS51))

Alternative Name: FFR / ANG2

Background: Fat Free, also known as ANG2, was identified though a yeast two-hybrid screen using VP53. It is thought to be a structural and functional homolog of the yeast protein VPS51, a protein that together with VPS52, VPS53, and VPS54 form the Golgi-associated retrograde protein (GARP) complex that mediates the tethering and fusion of endosome-derived transport carriers to the trans-Golgi network (TGN). Similar to depletion of any of the VPS52, VPS53, or VPS54, depletion of Fat Free using RNAi impairs protein retrieval to the TGN indicating that Fat Free is missing component of the GARP complex in most eukaryotes.Synonyms: Another new gene 2 protein, C11orf2, PP5382, Protein fat-free homolog

Molecular Weight: 86 kDa

Gene ID: 738

NCBI Accession: NP_037397