VPS51 antibody (AA 595-673) (Biotin)

Catalog No. ABIN7175325

Product Details anti-VPS51 Antibody (Biotin)

Target: VPS51 (Vacuolar Protein Sorting 51 Homolog (VPS51))

Binding Specificity: AA 595-673

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS51 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for VPS51

Target: VPS51 (Vacuolar Protein Sorting 51 Homolog (VPS51))

Alternative Name: VPS51 (VPS51 Products)

Synonyms: ANG2 antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, 1110014N23Rik antibody, 3110057M17Rik antibody, AI837850 antibody, Ffr antibody, VPS51 antibody, C29H11orf2 antibody, c11orf2 antibody, ffr antibody, fi30b05 antibody, wu:fi30b05 antibody, VPS51, GARP complex subunit antibody, VPS51 GARP complex subunit antibody, VPS51 GARP complex subunit S homeolog antibody, vacuolar protein sorting 51 homolog (S. cerevisiae) antibody, VPS51 antibody, Vps51 antibody, vps51.S antibody, vps51 antibody

Background:

Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Aliases: ANG2 antibody, ANG3 antibody, Another new gene 2 protein antibody, C11orf3 antibody, chromosome 11 open reading frame 2 antibody, Fat free homolog antibody, ffr antibody, FFR_HUMAN antibody, FFR|FLJ13879 antibody, FLJ36472 antibody, Protein fat-free homolog antibody, Vacuolar protein sorting 51 homolog antibody, VPS51 antibody

UniProt: Q9UID3