Transglutaminase 5 antibody (C-Term)

Catalog No. ABIN1450065

The Rabbit Polyclonal anti-Transglutaminase 5 antibody (ABIN1450065) specifically detects Transglutaminase 5 in WB, IF, IHC (p) and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Transglutaminase 5 antibody (C-Term) (ABIN1450065)

Target: Transglutaminase 5 (TGM5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Transglutaminase 5 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the carboxy terminus of Human TGM5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Transglutaminase 5

Target: Transglutaminase 5 (TGM5)

Alternative Name: Transglutaminase-5 (TGM5)

Background: Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies. TGM5 is also expressed in the human hair follicle. Defects in TGM5 are associated with acral peeling skin syndrome.Synonyms: Protein-glutamine gamma-glutamyltransferase 5, TGMX, TGX, TGase 5, TGase X, Transglutaminase X

Gene ID: 9333

NCBI Accession: NP_963925