Caldesmon antibody (pSer759)

Catalog No. ABIN1450476

This anti-Caldesmon antibody is a Rabbit Polyclonal antibody detecting Caldesmon in IHC and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for Caldesmon antibody (pSer759) (ABIN1450476)

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caldesmon antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Caldesmon Antibody

Binding Specificity: AA 725-774, pSer759

Specificity:

Caldesmon (Phospho-Ser759) Antibody detects endogenous levels of Caldesmon only when phosphorylated at Ser759.

PhosphorylationH:S759, M:S496, R:S497

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser759.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Alternative Name: Caldesmon

Background:

Synonyms: CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon

NCBI Gene Symbol: CALD1

Molecular Weight: 93 kDa

Gene ID: 800

OMIM: 114213

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction