RRM1 antibody (AA 246-792)

Catalog No. ABIN1500769

This Rabbit Polyclonal antibody specifically detects RRM1 in WB, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RRM1 antibody (AA 246-792) (ABIN1500769)

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RRM1 Antibody

Binding Specificity: AA 246-792

Specificity: Human RRM1

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse, Rat (97%) Bovine (95%) Chicken (92%).

Purification: Immunoaffinity purified

Immunogen: Recombinant fragment corresponding to a region within amino acids 246 and 792 of RRM1 (SwissProt P23921). Percent identity by BLAST analysis: Human (100%), Mouse, Rat (97%), Bovine (95%), Chicken (92%).

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (1:100 - 1:1000), WB (1:500 - 1:3000)

Usage: Suggested starting dilutions are as follows: Western blot: 1:500-1:3000, IHC-Paraffin: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10 mM Citrate buffer (  pH 6.0) or Tris-EDTA buffer (  pH 8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7, 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and freeze at -20°C. Avoid freeze-thaw cycles.

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: R1 / RRM1

Background: Name/Gene ID: RRM1

Synonyms: RRM1, R1, Ribonucleotide reductase M1, RR1, RIR1

Gene ID: 6240

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity