STIP1 antibody (AA 1-300)

Catalog No. ABIN3021759

The Rabbit Polyclonal anti-STIP1 antibody has been validated for WB, IHC and IF. It is suitable to detect STIP1 in samples from Human.

Quick Overview for STIP1 antibody (AA 1-300) (ABIN3021759)

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-STIP1 Antibody

Binding Specificity: AA 1-300

Sequence: MEQVNELKEK GNKALSVGNI DDALQCYSEA IKLDPHNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNPQLKE GLQNMEARLA ERKFMNPFNM PNLYQKLESD PRTRTLLSDP TYRELIEQLR NKPSDLGTKL QDPRIMTTLS VLLGVDLGSM DEEEEIATPP PPPPPKKETK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDTALKHYDK AKELDPTNMT YITNQAAVYF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA

Cross-Reactivity: Human, Monkey, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human STIP1 (NP_006810.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STIP1

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Alternative Name: STIP1

Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A, MIM 140550) and HSP90 (see HSP90AA1, MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],STIP1,HEL-S-94n,HOP,IEF-SSP-3521,P60,STI1,STI1L,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Neuroscience,Neurodegenerative Diseases,STIP1

Molecular Weight: 59 kDa/62 kDa/68 kDa

Gene ID: 10963

UniProt: P31948