ITPR2 antibody (C-Term)

Catalog No. ABIN1735930

The Rabbit Polyclonal anti-ITPR2 antibody has been validated for IHC, ELISA and WB. It is suitable to detect ITPR2 in samples from Rat.

Quick Overview for ITPR2 antibody (C-Term) (ABIN1735930)

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Product Details anti-ITPR2 Antibody

Binding Specificity: C-Term

Specificity: Reacts with rat 307 kDa IP3R-2 protein

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): May cross-reacts with mouse and human proteins due tosequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of rat IP3R-2 protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- WB : 1/100 to 1/1000 - IHC : 1/50 to 1/200

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for ITPR2

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Alternative Name: Inositol 1,4,5-Trisphosphate Receptor Type 2

Background: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA

Gene ID: 81678

UniProt: P29995

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma