Acetyl-CoA Carboxylase alpha antibody (pSer80)

Catalog No. ABIN1531254

This Rabbit Polyclonal antibody specifically detects Acetyl-CoA Carboxylase alpha in WB, IHC, ELISA. It exhibits reactivity toward Human, Mouse, Rat.

Quick Overview for Acetyl-CoA Carboxylase alpha antibody (pSer80) (ABIN1531254)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Acetyl-CoA Carboxylase alpha Antibody

Binding Specificity: AA 46-95, pSer80

Specificity:

ACC1 (Phospho-Ser80) Antibody detects endogenous levels of ACC1 only when phosphorylated at Ser80.

PhosphorylationH:S80 M:S79 R:S79

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ACC1 around the phosphorylation site of Ser80.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.160556 (NCBI Gene Symbol: ACACA)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Alternative Name: ACC1

Background:

Synonyms: ACAC, ACACA, ACC-alpha, ACCA, Acetyl-CoA carboxylase 1,

NCBI Gene Symbol: ACACA

Molecular Weight: 265 kDa

Gene ID: 31

OMIM: 200350

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect