alpha Adducin antibody (pThr445)

Catalog No. ABIN1531295

The Rabbit Polyclonal anti-alpha Adducin antibody (ABIN1531295) specifically detects alpha Adducin in IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for alpha Adducin antibody (pThr445) (ABIN1531295)

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Adducin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-alpha Adducin Antibody

Binding Specificity: AA 411-460, pThr445

Specificity:

ADD1 (Phospho-Thr445) Antibody detects endogenous levels of ADD1 only when phosphorylated at Thr445.

PhosphorylationH:T445 M:T445 R:T445

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADD1 around the phosphorylation site of Thr445.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.183706, Hs.701490 (NCBI Gene Symbol: ADD1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for alpha Adducin

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Alternative Name: ADD1

Background:

Synonyms: Alpha-adducin, Erythrocyte adducin subunit alpha , ADD1 , ADDA

NCBI Gene Symbol: ADD1

Molecular Weight: 80 kDa

Gene ID: 118

OMIM: 102680

UniProt: P35611

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling