alpha Adducin antibody (pThr445)

Catalog No. ABIN1531295

This anti-alpha Adducin antibody is a Rabbit Polyclonal antibody detecting alpha Adducin in IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for alpha Adducin antibody (pThr445) (ABIN1531295)

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Adducin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-alpha Adducin Antibody

Binding Specificity: AA 411-460, pThr445

Specificity:

ADD1 (Phospho-Thr445) Antibody detects endogenous levels of ADD1 only when phosphorylated at Thr445.

PhosphorylationH:T445 M:T445 R:T445

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADD1 around the phosphorylation site of Thr445.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.183706, Hs.701490 (NCBI Gene Symbol: ADD1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for alpha Adducin

Target: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Alternative Name: ADD1

Background:

Synonyms: Alpha-adducin, Erythrocyte adducin subunit alpha , ADD1 , ADDA

NCBI Gene Symbol: ADD1

Molecular Weight: 80 kDa

Gene ID: 118

OMIM: 102680

UniProt: P35611

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling