Caldesmon antibody (pSer789)

Catalog No. ABIN1531304

Product Details anti-Caldesmon Antibody

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Binding Specificity: AA 744-793, pSer789

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caldesmon antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Specificity:

Caldesmon (Phospho-Ser789) Antibody detects endogenous levels of Caldesmon only when phosphorylated at Ser789.

PhosphorylationH:S789 M:S560 R:S534

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser789.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.490203 (NCBI Gene Symbol: CALD1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Alternative Name: Caldesmon (CALD1 Products)

Background:

Synonyms: CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon

NCBI Gene Symbol: CALD1

Molecular Weight: 93 kDa

Gene ID: 800

OMIM: 114213

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction