SYK antibody (pTyr323)

Catalog No. ABIN1531397

This anti-SYK antibody is a Rabbit Polyclonal antibody detecting SYK in WB, IHC, ELISA and IF. Suitable for Human, Mouse and Rat.

Quick Overview for SYK antibody (pTyr323) (ABIN1531397)

Target: SYK (Spleen tyrosine Kinase (SYK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-SYK Antibody

Binding Specificity: AA 289-338, pTyr323

Specificity:

SYK (Phospho-Tyr323) Antibody detects endogenous levels of SYK only when phosphorylated at Tyr323.

PhosphorylationH:Y323 M:Y317 R:Y317

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr323.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000

Comment:

Unigene-Number: Hs.371720 (NCBI Gene Symbol: SYK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for SYK

Target: SYK (Spleen tyrosine Kinase (SYK))

Alternative Name: SYK

Background:

Synonyms: kinase Syk, KSYK, Spleen tyrosine kinase, SYK

NCBI Gene Symbol: SYK

Molecular Weight: 72 kDa

Gene ID: 6850

OMIM: 600085

UniProt: P43405

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling