NKX2-1 antibody (pSer113)

Catalog No. ABIN1531400

This anti-NKX2-1 antibody is a Rabbit Polyclonal antibody detecting NKX2-1 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for NKX2-1 antibody (pSer113) (ABIN1531400)

Target: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX2-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NKX2-1 Antibody

Binding Specificity: AA 79-128, pSer113

Specificity:

TEBP (Phospho-Ser113) Antibody detects endogenous levels of TEBP only when phosphorylated at Ser113.

PhosphorylationH:S113 M:S113 R:S245

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TEBP around the phosphorylation site of Ser113.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.50425 (NCBI Gene Symbol: PTGES3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for NKX2-1

Target: NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Alternative Name: TEBP

Background:

Synonyms: Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES, Telomerase-binding protein p23, Hsp90 co-chaperone, Progesterone receptor complex p23, PTGES3P23, TEBP

NCBI Gene Symbol: PTGES3

Molecular Weight: 18 kDa

Gene ID: 10728

OMIM: 607061

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour