ACLY antibody (pSer455)

Catalog No. ABIN1531422

The Rabbit Polyclonal anti-ACLY antibody (ABIN1531422) specifically detects ACLY in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ACLY antibody (pSer455) (ABIN1531422)

Target: ACLY (ATP Citrate Lyase (ACLY))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACLY antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ACLY Antibody

Binding Specificity: AA 420-469, pSer455

Specificity:

ATP-Citrate Lyase (Phospho-Ser454) Antibody detects endogenous levels of ATP-Citrate Lyase only when phosphorylated at Ser454.

PhosphorylationH:S455 M:S455 R:S454

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase around the phosphorylation site of Ser454.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.387567 (NCBI Gene Symbol: ACLY)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ACLY

Target: ACLY (ATP Citrate Lyase (ACLY))

Alternative Name: ATP-Citrate Lyase

Background:

Synonyms: ATP-citrate (pro-S-)-lyase, ATP-citrate lyase, Citrate cleavage enzyme,

NCBI Gene Symbol: ACLY

Molecular Weight: 120 kDa

Gene ID: 47

OMIM: 108728

UniProt: P53396

Pathways: Warburg Effect